Human egg cells are imperfect surprisingly often

More than 7% of human oocytes contain at least one exchangeless chromosome pair, demonstrating a remarkably high level of meiotic recombination failure, finds a new study. The findings suggest that right from the get-go of human egg cell development, a striking proportion of oocytes are predestined to be chromosomally abnormal. But the frequency of exchangeless chromosomes is not affected by maternal age.

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